AIRCARRUS project aims to provide a disruptive delivery service of goods, payloads, and medical lifesaving supplies utilizing a fully autonomous artificially intelligent aerial delivery system using drones/RPAS. The AIRCARRUS project solves the transportation challenges of purveying goods and emergency services to regions of limited urban infrastructure, ocean vessels, high traffic urban areas, and the delivery of time sensitive lifesaving goods. There is real need and open tenders for a delivery system like the AIRCARRUS from clients such as ocean vessel operators, to developing nations that are lacking roads or are geographically challenged. The use of the AIRCARRUS system in the future is also suitable for developed urban areasthat have high traffic congestion and require new transportation systems. The engineering solution approach for the AIRCARRUS is completely disruptive since it focuses on a fully autonomous ground to air system that requires little or no operator interactions using a smart ground station. Full autonomous operations will drive higher delivery volumes while lowering the costs per delivery making the solution more and more attractive to new users.